Are Membranes Hydrophilic Or Hydrophobic
Abstract
In this study, an asymmetric wettable blended wound dressing consists of hydrophobic polyvinylidene fluoride (PVDF) outer layer and a hydrophilic polydopamine (PDA) coated Ag nanoparticles (Ag NPs)/PVDF layer (PVDF-Ag-PDA) was successfully prepared through electrospinning and PDA blanket. The results evidence that the contact angle of the PVDF surface is 132.8°, while the PDA-coated surface is nearly 0°, indicating an asymmetric wettability. The highly hydrophilic PVDF-Ag-PDA layer tin can significantly reduce bacterial growth, while the PVDF layer with a small pore size and loftier hydrophobicity can prevent bacterial adherence. In addition, cytotoxic assays showed that PVDF/PVDF-Ag-PDA nowadays a high prison cell viability per centum (above eighty %), which is attributed to that the thin layer of PDA can alleviate the cytotoxicity of Ag NPs. Therefore, the Janus wound dressing noted every bit PVDF/PVDF-Ag-PDA has the potential for applied applications with the advantages mentioned above.
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Acknowledgement
The authors sincerely thank for the financial back up from the National Natural Scientific discipline Foundation of China [Grant No. 52075277 and No. 21805147], the Clinical Medicine + X Research Project of Affiliated Hospital of Qingdao University (NO. QDFY+X2021007).
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Vocal, M., Zhao, Q., Wang, X. et al. A Hydrophilic/Hydrophobic Janus Membrane Used as Wound Dressings with Enhanced Antibacterial Properties. Fibers Polym 23, 2511–2516 (2022). https://doi.org/10.1007/s12221-022-0127-1
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DOI : https://doi.org/10.1007/s12221-022-0127-one
Keywords
- Janus
- Polydopamine coating
- Anti-bacteria
- PVDF
- Ag NPs
Are Membranes Hydrophilic Or Hydrophobic,
Source: https://link.springer.com/article/10.1007/s12221-022-0127-1
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